Infused with extra-soothing rose extract, C. O. Bigelow's famous Rose Salve helps ease irritation and condition the skin use on the lips, face, cuticles, elbows, and knees for instant relief. About C. O. Bigelow Celebrated as the oldest apothecary in America, C. O. Bigelow has supplied a unique assortment of remedies and beauty products since 1838. Intent on being a source of discovery and learning, they continue to produce and house rare and natural goods crafted for your well-being.