Pour 23 shakes (about a quarter size) of the essence into the palm of your hand. Press together to wet both hands. Gently press the essence over your face and neck for 1 minute, ensuring even coverage. Continue pressing until it is fully absorbed into your skin. This essence can be used twice daily. Applying after any cleansers/toners and before any serums/moisturizers is recommended. Key Ingredients: PITERA™ Improves skin's natural regeneration, for youthful skin Ingredients: Galactomyces Ferment Filtrate (PITERA™), Butylene Glycol, Pentylene Glycol, Water, Sodium Benzoate, Methylparaben, Sorbic Acid Skin type: Normal, Dry, Combination, Oily Skin concern: Dark Spots, Fine Lines/Wrinkles, Uneven Texture Research/Clinical Results: In an 11year longitudinal study with 108 subjects: PITERA™ was shown to diminish visible skin damage and signs of aging (fine lines, wrinkles, sun spots, dullness, texture, dryness) by up to 10 years with just 1 year of PITERA™ regimen use. In a 28day consumer agreement study with 65 participants: Skin felt moisturized and smooth after 3 days Skin looked and felt softer and firmer after 1 week Users saw improved skin texture and reduced fine lines and wrinkles appearance after 2 weeks Skin looked radiant after 28 days In a clinical study with 272 women: Women who started using the Facial Treatment Essence in their 20s looked significantly younger in their 30s and 40s.