SK-II RNA Essence in Beauty: NA. SK-II RNA Essence in Beauty: NA. SK-II R.N.A. Power Essence brings you the next level of firmness. This powerful serum increases lengthwise-crosswise firmness while minimizing the appearance of pores for a fresh, youthful looking glow. Each drop fills lines and gaps in the skin, making it firm, resilient, and plump.. Pitera is rich in vitamins, amino acids, and minerals that improve the skin's natural rejuvenation process. Lightweight, fluid texture absorbs easily into the skin. Suitable for all skin types. 1.7 fl oz. Apply a dropper full of essence to the forehead, cheeks, and chin; then gently massage into the skin, starting from the center. Use with SK-II R.N.A Power Cream for best results. SKTW-WU27. 730870157794. In the 1970s, SK-II scientists began a fervent quest to uncover a skincare ingredient that would make beautiful skin a reality. Researching a myriad of possibilities ranging from Chinese herbs to hot spring water - the secret they were looking for eluded them for a long time. It was only by a chance encounter that the scientists observed the soft and youthful hands of aged sake brewers. The astounding sight of the wrinkled faces of aged sake brewers contrasting their soft youthful hands remained seared in the memories of the SK-II scientists. Back in the confines of the laboratory, they surmised that the secret must lie in the yeast that the brewers' hands were in constant contact with during the sake fermentation process. And that is how an exhaustive research of over 350 yeast strains began. Poring over even the smallest singular detail, the scientists spent over five years isolating the single yeast strain that held the secret to crystal clear skin. It was the birth of a miracle, a beauty revolution that would soon come to be known as PITERA.